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Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice
Fetal growth restriction, or low birth weight, is a strong determinant for eventual obesity and type 2 diabetes. Clinical studies suggest placental mechanistic target of rapamycin (mTOR) signaling regulates fetal birth weight and the metabolic health trajectory of the offspring. In the current study...
Autores principales: | Akhaphong, Brian, Baumann, Daniel C., Beetch, Megan, Lockridge, Amber D., Jo, Seokwon, Wong, Alicia, Zemanovic, Tate, Mohan, Ramkumar, Fondevilla, Danica L., Sia, Michelle, Pineda-Cortel, Maria Ruth B., Alejandro, Emilyn U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410096/ https://www.ncbi.nlm.nih.gov/pubmed/34032632 http://dx.doi.org/10.1172/jci.insight.149271 |
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