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Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism

Kisspeptin (encoded by Kiss1), a neuropeptide critically involved in neuroendocrine regulation of reproduction, is primarily synthesized in two hypothalamic nuclei: the anteroventral periventricular nucleus (AVPV) and arcuate nucleus (ARC). AVPV kisspeptin is thought to regulate the estrogen-induced...

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Detalles Bibliográficos
Autores principales: Nandankar, Nimisha, Negrón, Ariel L., Wolfe, Andrew, Levine, Jon E., Radovick, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410100/
https://www.ncbi.nlm.nih.gov/pubmed/34181485
http://dx.doi.org/10.1152/ajpendo.00088.2021