DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy

Pulmonary hypertension (PH) is associated with structural remodeling of pulmonary arteries (PAs) because of excessive proliferation of fibroblasts, endothelial cells, and smooth muscle cells (SMCs). The peptide hormone angiotensin II (ANG II) contributes to pulmonary vascular remodeling, in part, th...

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Detalles Bibliográficos
Autores principales: Ferguson, Bradley S., Wennersten, Sara A., Demos-Davies, Kimberly M., Rubino, Marcello, Robinson, Emma L., Cavasin, Maria A., Stratton, Matthew S., Kidger, Andrew M., Hu, Tianjing, Keyse, Stephen M., McKnight, Robert A., Lane, Robert H., Nozik, Eva S., Weiser-Evans, Mary C. M., McKinsey, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Rapid Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410116/
https://www.ncbi.nlm.nih.gov/pubmed/34142888
http://dx.doi.org/10.1152/ajpheart.00115.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410116/
https://www.ncbi.nlm.nih.gov/pubmed/34142888
http://dx.doi.org/10.1152/ajpheart.00115.2021

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