Mechanism of lncRNA-ANRIL/miR-181b in autophagy of cardiomyocytes in mice with uremia by targeting ATG5

OBJECTIVES: This study is to investigate whether the cardiac microvascular endothelial cells (CMECs) can regulate the autophagy of cardiomyocytes (CMs) by secreting lncRNA-ANRIL/miR-181b exosomes, thus participating in the occurrence of uremic cardiovascular disease (CVD). METHODS: A 5/6 nephrectomy...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Chen, Jing, Wang, Minmin, Yu, Rizhen, Zou, Wenly, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410126/
https://www.ncbi.nlm.nih.gov/pubmed/34469488
http://dx.doi.org/10.1371/journal.pone.0256734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410126/
https://www.ncbi.nlm.nih.gov/pubmed/34469488
http://dx.doi.org/10.1371/journal.pone.0256734

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