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Predicted pH-dependent stability of SARS-CoV-2 spike protein trimer from interfacial acidic groups
Transition between receptor binding domain (RBD) up and down forms of the SARS-CoV-2 spike protein trimer is coupled to receptor binding and is one route by which variants can alter viral properties. It is becoming apparent that key roles in the transition are played by pH and a more compact closed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410215/ https://www.ncbi.nlm.nih.gov/pubmed/34490059 http://dx.doi.org/10.1016/j.csbj.2021.08.049 |