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Early-life experiences altered the maturation of the lateral habenula in mouse models, resulting in behavioural disorders in adulthood

BACKGROUND: Abnormally high activity in the lateral habenula causes anxiety- or depression-like behaviours in animal experimental models. It has also been reported in humans that excessive stress in early life is correlated with the onset of psychiatric disorders in adults. These findings raise the...

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Detalles Bibliográficos
Autores principales: Nakamura, Tomoya, Kurosaki, Kohei, Kanemoto, Munenori, Sasahara, Masakiyo, Ichijo, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Joule Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410472/
https://www.ncbi.nlm.nih.gov/pubmed/34346201
http://dx.doi.org/10.1503/jpn.200226