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KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer

MLL3 histone methyltransferase, encoded by the KMT2C gene, is a tumor suppressor that has an essential role in cell‐type‐specific gene expression. We evaluated the prognostic significance of KMT2C promoter methylation as a circulating epigenetic biomarker in plasma cell‐free DNA (cfDNA) in non‐small...

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Detalles Bibliográficos
Autores principales: Mastoraki, Sofia, Balgkouranidou, Ioanna, Tsaroucha, Emily, Klinakis, Apostolos, Georgoulias, Vassilis, Lianidou, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410531/
https://www.ncbi.nlm.nih.gov/pubmed/33159839
http://dx.doi.org/10.1002/1878-0261.12848