Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia

Long-term treatment with 6-thioguanine (6-TG) for pediatric acute lymphoblastic leukemia (ALL) is associated with high rates of hepatic sinusoidal obstruction syndrome (SOS). Nevertheless, current treatment continues to use short-term applications of 6-TG with only sparse information on toxicity. 6-...

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Detalles Bibliográficos
Autores principales: Stanulla, Martin, Schaeffeler, Elke, Möricke, Anja, Buchmann, Swantje, Zimmermann, Martin, Igel, Svitlana, Schmiegelow, Kjeld, Flotho, Christian, Hartmann, Hans, Illsinger, Sabine, Sauerbrey, Axel, Junk, Stefanie V., Schütte, Peter, Hinze, Laura, Lauten, Melchior, Modlich, Simon, Kolb, Reinhard, Rossig, Claudia, Schwabe, Georg, Gnekow, Astrid K., Fleischhack, Gudrun, Schlegel, Paul Gerhard, Schünemann, Holger J., Kratz, Christian P., Cario, Gunnar, Schrappe, Martin, Schwab, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410596/
https://www.ncbi.nlm.nih.gov/pubmed/33714975
http://dx.doi.org/10.1038/s41375-021-01203-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410596/
https://www.ncbi.nlm.nih.gov/pubmed/33714975
http://dx.doi.org/10.1038/s41375-021-01203-7

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