cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila

Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that produces the second messenger cG[2′–5′]pA[3′–5′]p (2′3′-cGAMP) and controls activation of innate immunity in mammalian cells(1–5). Animal genomes typically encode multiple proteins with predicted homology to cGAS(6–10), but the function o...

Descripción completa

Detalles Bibliográficos
Autores principales: Slavik, Kailey M., Morehouse, Benjamin R., Ragucci, Adelyn E., Zhou, Wen, Ai, Xianlong, Chen, Yuqiang, Li, Lihua, Wei, Ziming, Bähre, Heike, König, Martin, Seifert, Roland, Lee, Amy S. Y., Cai, Hua, Imler, Jean-Luc, Kranzusch, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410604/
https://www.ncbi.nlm.nih.gov/pubmed/34261127
http://dx.doi.org/10.1038/s41586-021-03743-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410604/
https://www.ncbi.nlm.nih.gov/pubmed/34261127
http://dx.doi.org/10.1038/s41586-021-03743-5

Ejemplares similares