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Reduced sociability and social agency encoding in adult Shank3 mutant mice are restored through gene re-expression in real-time

Despite a growing understanding of the molecular and developmental basis of autism spectrum disorder (ASD), how the neuronal encoding of social information is precisely disrupted in ASD and whether it contributes to abnormal social behavior remains unclear. Here, we disrupted and then restored expre...

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Detalles Bibliográficos
Autores principales: Lee, Daniel K, Li, S William, Bounni, Firas, Friedman, Gabriel, Jamali, Mohsen, Strahs, Leah, Zelinger, Omer, Gabrieli, Pauline, Stankovich, Michael A, Demaree, Jack, Williams, Ziv M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410666/
https://www.ncbi.nlm.nih.gov/pubmed/34253921
http://dx.doi.org/10.1038/s41593-021-00888-4