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Follicular T Helper and Breg Cell Balance in Severe Allergic Asthma Before and After Omalizumab Therapy

BACKGROUND: Severe allergic asthma (SAA) is based on type 2 (T2-high) immune responses to allergens promoting type 2 T helper (Th2) cell cytokine responses and production of IgE antibodies. Omalizumab was the first biological drug licensed for clinical use in the management of IgE-mediated SAA. Desp...

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Detalles Bibliográficos
Autores principales: Bergantini, Laura, d’Alessandro, Miriana, Cameli, Paolo, Pianigiani, Tommaso, Fanetti, Matteo, Sestini, Piersante, Bargagli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410727/
https://www.ncbi.nlm.nih.gov/pubmed/34342843
http://dx.doi.org/10.1007/s40291-021-00545-3