Cyclodextrin Complex Formation with Water-Soluble Drugs: Conclusions from Isothermal Titration Calorimetry and Molecular Modeling

Cyclodextrin (CD) complexes are frequently used for enhancing the solubility or absorption of poorly water-soluble drugs. On the contrary, little is known about their complex formation with water-soluble drugs. Here, we have studied the interaction between 2-hydroxypropyl β-CD (HPβCD) and three wate...

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Detalles Bibliográficos
Autores principales: Shalaby, Karim S., Ismail, Muhammad I., Lamprecht, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410728/
https://www.ncbi.nlm.nih.gov/pubmed/34468866
http://dx.doi.org/10.1208/s12249-021-02040-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410728/
https://www.ncbi.nlm.nih.gov/pubmed/34468866
http://dx.doi.org/10.1208/s12249-021-02040-8

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