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Degradation of lipid droplets by chimeric autophagy-tethering compounds

Degrading pathogenic proteins by degrader technologies such as PROTACs (proteolysis-targeting chimeras) provides promising therapeutic strategies, but selective degradation of non-protein pathogenic biomolecules has been challenging. Here, we demonstrate a novel strategy to degrade non-protein biomo...

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Detalles Bibliográficos
Autores principales: Fu, Yuhua, Chen, Ningxie, Wang, Ziying, Luo, Shouqing, Ding, Yu, Lu, Boxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410765/
https://www.ncbi.nlm.nih.gov/pubmed/34239073
http://dx.doi.org/10.1038/s41422-021-00532-7