Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Dyslipidemia and resulting lipotoxicity are pathologic signatures of metabolic syndrome and type 2 diabetes. Excess lipid causes cell dysfunction and induces cell death through pleiotropic mechanisms that link to oxidative stress. However, pathways that regulate the response to metabolic stress are...

Descripción completa

Detalles Bibliográficos
Autores principales: Sletten, Arthur C., Davidson, Jessica W., Yagabasan, Busra, Moores, Samantha, Schwaiger-Haber, Michaela, Fujiwara, Hideji, Gale, Sarah, Jiang, Xuntian, Sidhu, Rohini, Gelman, Susan J., Zhao, Shuang, Patti, Gary J., Ory, Daniel S., Schaffer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410784/
https://www.ncbi.nlm.nih.gov/pubmed/34471131
http://dx.doi.org/10.1038/s41467-021-25457-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410784/
https://www.ncbi.nlm.nih.gov/pubmed/34471131
http://dx.doi.org/10.1038/s41467-021-25457-y

Ejemplares similares