Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Dyslipidemia and resulting lipotoxicity are pathologic signatures of metabolic syndrome and type 2 diabetes. Excess lipid causes cell dysfunction and induces cell death through pleiotropic mechanisms that link to oxidative stress. However, pathways that regulate the response to metabolic stress are...

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Detalles Bibliográficos
Autores principales: Sletten, Arthur C., Davidson, Jessica W., Yagabasan, Busra, Moores, Samantha, Schwaiger-Haber, Michaela, Fujiwara, Hideji, Gale, Sarah, Jiang, Xuntian, Sidhu, Rohini, Gelman, Susan J., Zhao, Shuang, Patti, Gary J., Ory, Daniel S., Schaffer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410784/
https://www.ncbi.nlm.nih.gov/pubmed/34471131
http://dx.doi.org/10.1038/s41467-021-25457-y

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