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Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy

Uremic cardiomyopathy is characterized by diastolic dysfunction (DD), left ventricular hypertrophy (LVH), and fibrosis. Angiotensin-II plays a major role in the development of uremic cardiomyopathy via nitro-oxidative and inflammatory mechanisms. In heart failure, the beta-3 adrenergic receptor (β3-...

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Detalles Bibliográficos
Autores principales: Kovács, Zsuzsanna Z. A., Szűcs, Gergő, Freiwan, Marah, Kovács, Mónika G., Márványkövi, Fanni M., Dinh, Hoa, Siska, Andrea, Farkas, Katalin, Kovács, Ferenc, Kriston, András, Horváth, Péter, Kővári, Bence, Cserni, Bálint Gábor, Cserni, Gábor, Földesi, Imre, Csont, Tamás, Sárközy, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410807/
https://www.ncbi.nlm.nih.gov/pubmed/34471171
http://dx.doi.org/10.1038/s41598-021-96815-5