Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents

The rodents of hystricomorpha and sciuromorpha suborders exhibit remarkably lower incidence of cancer. The underlying genetic basis remains obscure. We report a convergent evolutionary split of human 3p21.31, a locus hosting a large number of tumour-suppressor genes (TSGs) and frequently deleted in...

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Detalles Bibliográficos
Autores principales: Jain, Yachna, Chandradoss, Keerthivasan Raanin, A. V., Anjoom, Bhattacharya, Jui, Lal, Mohan, Bagadia, Meenakshi, Singh, Harpreet, Sandhu, Kuljeet Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410860/
https://www.ncbi.nlm.nih.gov/pubmed/34471123
http://dx.doi.org/10.1038/s41514-021-00072-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410860/
https://www.ncbi.nlm.nih.gov/pubmed/34471123
http://dx.doi.org/10.1038/s41514-021-00072-9

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