Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation

The autophagic degradation of misfolded and ubiquitinated proteins is important for cellular homeostasis. In this process, which is governed by cargo receptors, ubiquitinated proteins are condensed into larger structures and subsequently become targets for the autophagy machinery. Here we employ in...

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Detalles Bibliográficos
Autores principales: Turco, Eleonora, Savova, Adriana, Gere, Flora, Ferrari, Luca, Romanov, Julia, Schuschnig, Martina, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410870/
https://www.ncbi.nlm.nih.gov/pubmed/34471133
http://dx.doi.org/10.1038/s41467-021-25572-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410870/
https://www.ncbi.nlm.nih.gov/pubmed/34471133
http://dx.doi.org/10.1038/s41467-021-25572-w

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