Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression

INTRODUCTION: Sporadic Alzheimer's disease (AD) is strongly correlated with impaired brain glucose metabolism, which may affect AD onset and progression. Ketolysis has been suggested as an alternative pathway to fuel the brain. METHODS: RNA‐seq profiles of post mortem AD brains were used to det...

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Detalles Bibliográficos
Autores principales: Saito, Erin R., Miller, Justin B., Harari, Oscar, Cruchaga, Carlos, Mihindukulasuriya, Kathie A., Kauwe, John S. K., Bikman, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410881/
https://www.ncbi.nlm.nih.gov/pubmed/33650792
http://dx.doi.org/10.1002/alz.12310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410881/
https://www.ncbi.nlm.nih.gov/pubmed/33650792
http://dx.doi.org/10.1002/alz.12310

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