Cargando…
Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression
INTRODUCTION: Sporadic Alzheimer's disease (AD) is strongly correlated with impaired brain glucose metabolism, which may affect AD onset and progression. Ketolysis has been suggested as an alternative pathway to fuel the brain. METHODS: RNA‐seq profiles of post mortem AD brains were used to det...
Autores principales: | Saito, Erin R., Miller, Justin B., Harari, Oscar, Cruchaga, Carlos, Mihindukulasuriya, Kathie A., Kauwe, John S. K., Bikman, Benjamin T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410881/ https://www.ncbi.nlm.nih.gov/pubmed/33650792 http://dx.doi.org/10.1002/alz.12310 |
Ejemplares similares
-
Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy
por: Chang, Howard T, et al.
Publicado: (2013) -
The Association of Ketolytic Enzymes Gene Expression Levels with Mitochondrial Activity and Content in Oral Squamous Cell Carcinoma
por: Yousefi, Mahdisa, et al.
Publicado: (2022) -
An 8-Week Ketogenic Diet Alternated Interleukin-6, Ketolytic and Lipolytic Gene Expression, and Enhanced Exercise Capacity in Mice
por: Ma, Sihui, et al.
Publicado: (2018) -
Locus specific endogenous retroviral expression associated with Alzheimer’s disease
por: Dawson, Tyson, et al.
Publicado: (2023) -
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo
por: Zhang, Jie, et al.
Publicado: (2018)