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Lack of efficacy of a partial adenosine A1 receptor agonist in neuropathic pain models in mice

Previous studies suggest that adenosine A(1) receptors (A(1)R) modulate the processing of pain. The aim of this study was to characterize the distribution of A(1)R in nociceptive tissues and to evaluate whether targeting A(1)R with the partial agonist capadenoson may reduce neuropathic pain in mice....

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Detalles Bibliográficos
Autores principales: Metzner, Katharina, Gross, Tilman, Balzulat, Annika, Wack, Gesine, Lu, Ruirui, Schmidtko, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410902/
https://www.ncbi.nlm.nih.gov/pubmed/34313915
http://dx.doi.org/10.1007/s11302-021-09806-6