HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine

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As a robust antagonist of myostatin (MSTN), follistatin (FST) is an important regulator of skeletal muscle development, and the delivery of FST to muscle tissue represents a potential therapeutic strategy for muscular dystrophies. The N terminus and FSI domain of FST are the functional domains for M...

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Detalles Bibliográficos
Autores principales: Li, Mengjing, Tang, Xiaochun, You, Wenni, Wang, Yanbing, Chen, Yiwu, Liu, Ying, Yuan, Hongming, Gao, Chuang, Chen, Xue, Xiao, Zhiwei, Ouyang, Hongsheng, Pang, Daxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411015/
https://www.ncbi.nlm.nih.gov/pubmed/34513293
http://dx.doi.org/10.1016/j.omtn.2021.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411015/
https://www.ncbi.nlm.nih.gov/pubmed/34513293
http://dx.doi.org/10.1016/j.omtn.2021.06.011

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