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Nrf2 induces Ucp1 expression in adipocytes in response to β3-AR stimulation and enhances oxygen consumption in high-fat diet-fed obese mice

Coldinduced norepinephrine activates β3-adrenergic receptors (β3-AR) to stimulate the kinase cascade and cAMP-response element-binding protein, leading to the induction of thermogenic gene expression including uncoupling protein 1 (Ucp1). Here, we showed that stimulation of the β3-AR by its agonists...

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Detalles Bibliográficos
Autores principales: Chang, Seo-Hyuk, Jang, Jaeyool, Oh, Seungjun, Yoon, Jung-Hoon, Jo, Dong-Gyu, Yun, Ui Jeong, Park, Kye Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411042/
https://www.ncbi.nlm.nih.gov/pubmed/33691909
http://dx.doi.org/10.5483/BMBRep.2021.54.8.023