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EBP1 regulates Suv39H1 stability via the ubiquitin-proteasome system in neural development

ErbB3-binding protein 1 (EBP1) is a multifunctional protein associated with neural development. Loss of Ebp1 leads to upregulation of the gene silencing unit suppressor of variegation 3-9 homolog 1 (Suv39H1)/DNA (cytosine 5)-methyltransferase (DNMT1). EBP1 directly binds to the promoter region of DN...

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Detalles Bibliográficos
Autores principales: Kim, Byeong-Seong, Ko, Hyo Rim, Hwang, Inwoo, Cho, Sung-Woo, Ahn, Jee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411044/
https://www.ncbi.nlm.nih.gov/pubmed/33691908
http://dx.doi.org/10.5483/BMBRep.2021.54.8.022