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Perspectives on immune checkpoint ligands: expression, regulation, and clinical implications

In the tumor microenvironment, immune checkpoint ligands (ICLs) must be expressed in order to trigger the inhibitory signal via immune checkpoint receptors (ICRs). Although ICL expression frequently occurs in a manner intrinsic to tumor cells, extrinsic factors derived from the tumor microenvironmen...

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Detalles Bibliográficos
Autores principales: Moon, Jihyun, Oh, Yoo Min, Ha, Sang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411045/
https://www.ncbi.nlm.nih.gov/pubmed/34078531
http://dx.doi.org/10.5483/BMBRep.2021.54.8.054