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The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies

Cofilins are important for the regulation of the actin cytoskeleton, sarcomere organization, and force production. The role of cofilin-1, the non-muscle-specific isoform, in muscle function remains unclear. Mutations in LMNA encoding A-type lamins, intermediate filament proteins of the nuclear envel...

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Detalles Bibliográficos
Autores principales: Vignier, Nicolas, Chatzifrangkeskou, Maria, Pinton, Luca, Wioland, Hugo, Marais, Thibaut, Lemaitre, Mégane, Le Dour, Caroline, Peccate, Cécile, Cardoso, Déborah, Schmitt, Alain, Wu, Wei, Biferi, Maria-Grazia, Naouar, Naïra, Macquart, Coline, Beuvin, Maud, Decostre, Valérie, Bonne, Gisèle, Romet-Lemonne, Guillaume, Worman, Howard J., Tedesco, Francesco Saverio, Jégou, Antoine, Muchir, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411111/
https://www.ncbi.nlm.nih.gov/pubmed/34433058
http://dx.doi.org/10.1016/j.celrep.2021.109601