Dual role for CXCL12 signaling in semilunar valve development

Cxcl12-null embryos have dysplastic, misaligned, and hyperplastic semilunar valves (SLVs). In this study, we show that CXCL12 signaling via its receptor CXCR4 fulfills distinct roles at different stages of SLV development, acting initially as a guidance cue to pattern cellular distribution within th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ridge, Liam A., Kewbank, Dania, Schütz, Dagmar, Stumm, Ralf, Scambler, Peter J., Ivins, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411116/
https://www.ncbi.nlm.nih.gov/pubmed/34433040
http://dx.doi.org/10.1016/j.celrep.2021.109610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411116/
https://www.ncbi.nlm.nih.gov/pubmed/34433040
http://dx.doi.org/10.1016/j.celrep.2021.109610

Ejemplares similares