Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches

Hematopoietic stem and progenitor cell (HSPC) engraftment after transplantation during anticancer treatment depends on support from the recipient bone marrow (BM) microenvironment. Here, by studying physiological homing of fetal HSPCs, we show the critical requirement of balanced local crosstalk wit...

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Detalles Bibliográficos
Autores principales: Mesnieres, Marion, Böhm, Anna-Marei, Peredo, Nicolas, Trompet, Dana, Valle-Tenney, Roger, Bajaj, Manmohan, Corthout, Nikky, Nefyodova, Elena, Cardoen, Ruben, Baatsen, Pieter, Munck, Sebastian, Nagy, Andras, Haigh, Jody J., Khurana, Satish, Verfaillie, Catherine M., Maes, Christa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411121/
https://www.ncbi.nlm.nih.gov/pubmed/34433017
http://dx.doi.org/10.1016/j.celrep.2021.109618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411121/
https://www.ncbi.nlm.nih.gov/pubmed/34433017
http://dx.doi.org/10.1016/j.celrep.2021.109618

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