Multiple basic amino acids in the cleavage site of H7N9 hemagglutinin contribute to high virulence in mice

BACKGROUND: Avian influenza A (H7N9) virus has caused more than 1,500 cases of human infection since its emergence in early 2013. Displaying little or no pathogenicity in poultry, but a 40% case-fatality rate in humans, five waves of H7N9 human infections occurred in China during 2013–2017, caused s...

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Detalles Bibliográficos
Autores principales: Song, Wenjun, Huang, Xiaofeng, Guan, Wenda, Chen, Pin, Wang, Pui, Zheng, Min, Li, Zhengtu, Wang, Yutao, Yang, Zifeng, Chen, Honglin, Wang, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411188/
https://www.ncbi.nlm.nih.gov/pubmed/34527306
http://dx.doi.org/10.21037/jtd-21-226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411188/
https://www.ncbi.nlm.nih.gov/pubmed/34527306
http://dx.doi.org/10.21037/jtd-21-226

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