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Contributions of HFE polymorphisms to brain and blood iron load, and their links to cognitive and motor function in healthy adults
BACKGROUND: Brain iron overload is linked to brain deterioration, and cognitive and motor impairment in neurodegenerative disorders and normal aging. Mutations in the HFE gene are associated with iron dyshomeostasis and are risk factors for peripheral iron overload. However, links to brain iron load...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411306/ https://www.ncbi.nlm.nih.gov/pubmed/34291615 http://dx.doi.org/10.1002/npr2.12197 |