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De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity

BACKGROUND: Gene expression-based subtyping has the potential to form a new paradigm for stratified treatment of colorectal cancer. However, current frameworks are based on the transcriptomic profiles of primary tumors, and metastatic heterogeneity is a challenge. Here we aimed to develop a de novo...

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Detalles Bibliográficos
Autores principales: Moosavi, Seyed H., Eide, Peter W., Eilertsen, Ina A., Brunsell, Tuva H., Berg, Kaja C. G., Røsok, Bård I., Brudvik, Kristoffer W., Bjørnbeth, Bjørn A., Guren, Marianne G., Nesbakken, Arild, Lothe, Ragnhild A., Sveen, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411513/
https://www.ncbi.nlm.nih.gov/pubmed/34470666
http://dx.doi.org/10.1186/s13073-021-00956-1