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De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
BACKGROUND: Gene expression-based subtyping has the potential to form a new paradigm for stratified treatment of colorectal cancer. However, current frameworks are based on the transcriptomic profiles of primary tumors, and metastatic heterogeneity is a challenge. Here we aimed to develop a de novo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411513/ https://www.ncbi.nlm.nih.gov/pubmed/34470666 http://dx.doi.org/10.1186/s13073-021-00956-1 |