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De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
BACKGROUND: Gene expression-based subtyping has the potential to form a new paradigm for stratified treatment of colorectal cancer. However, current frameworks are based on the transcriptomic profiles of primary tumors, and metastatic heterogeneity is a challenge. Here we aimed to develop a de novo...
Autores principales: | Moosavi, Seyed H., Eide, Peter W., Eilertsen, Ina A., Brunsell, Tuva H., Berg, Kaja C. G., Røsok, Bård I., Brudvik, Kristoffer W., Bjørnbeth, Bjørn A., Guren, Marianne G., Nesbakken, Arild, Lothe, Ragnhild A., Sveen, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411513/ https://www.ncbi.nlm.nih.gov/pubmed/34470666 http://dx.doi.org/10.1186/s13073-021-00956-1 |
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