In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1

BACKGROUND: Obtusofolin is the major active ingredient of Catsia tora L., which possesses the activity of improving eyesight and protecting the optic nerve. Investigation on the interaction of obtusofolin with cytochrome P450 enzymes (CYP450s) could provide a reference for the clinical application o...

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Detalles Bibliográficos
Autores principales: Liu, Na, Chen, Ping, Du, Xiaojun, Sun, Junxia, Han, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411522/
https://www.ncbi.nlm.nih.gov/pubmed/34470620
http://dx.doi.org/10.1186/s12906-021-03397-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411522/
https://www.ncbi.nlm.nih.gov/pubmed/34470620
http://dx.doi.org/10.1186/s12906-021-03397-w

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