Cargando…

Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males

Background: Hypoxia and inflammation are hallmarks of critical illness, related to multiple organ failure. A possible mechanism leading to multiple organ failure is hypoxia- or inflammation-induced down-regulation of the detoxifying glyoxalase system that clears dicarbonyl stress. The dicarbonyl met...

Descripción completa

Detalles Bibliográficos
Autores principales: G.H. Driessen, Rob, Kiers, Dorien, G. Schalkwijk, Casper, L.J.M. Scheijen, Jean, Gerretsen, Jelle, Pickkers, Peter, C.G. van de Poll, Marcel, C.C. van der Horst, Iwan, C.J.J. Bergmans, Dennis, Kox, Matthijs, C.T. van Bussel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411911/
https://www.ncbi.nlm.nih.gov/pubmed/34156474
http://dx.doi.org/10.1042/BSR20210954