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Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males

Background: Hypoxia and inflammation are hallmarks of critical illness, related to multiple organ failure. A possible mechanism leading to multiple organ failure is hypoxia- or inflammation-induced down-regulation of the detoxifying glyoxalase system that clears dicarbonyl stress. The dicarbonyl met...

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Detalles Bibliográficos
Autores principales:	G.H. Driessen, Rob, Kiers, Dorien, G. Schalkwijk, Casper, L.J.M. Scheijen, Jean, Gerretsen, Jelle, Pickkers, Peter, C.G. van de Poll, Marcel, C.C. van der Horst, Iwan, C.J.J. Bergmans, Dennis, Kox, Matthijs, C.T. van Bussel, Bas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Diabetes & Metabolic Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411911/ https://www.ncbi.nlm.nih.gov/pubmed/34156474 http://dx.doi.org/10.1042/BSR20210954

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