Reduction in miR‐219 expression underlies cellular pathogenesis of oligodendrocytes in a mouse model of Krabbe disease

Krabbe disease (KD), also known as globoid cell leukodystrophy, is an inherited demyelinating disease caused by the deficiency of lysosomal galactosylceramidase (GALC) activity. Most of the patients are characterized by early‐onset cerebral demyelination with apoptotic oligodendrocyte (OL) death and...

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Detalles Bibliográficos
Autores principales: Inamura, Naoko, Go, Shinji, Watanabe, Takashi, Takase, Hiroshi, Takakura, Nobuyuki, Nakayama, Atsuo, Takebayashi, Hirohide, Matsuda, Junko, Enokido, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412087/
https://www.ncbi.nlm.nih.gov/pubmed/33822434
http://dx.doi.org/10.1111/bpa.12951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412087/
https://www.ncbi.nlm.nih.gov/pubmed/33822434
http://dx.doi.org/10.1111/bpa.12951

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