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The presence of TIM‐3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status

Diffuse gliomas are aggressive brain tumors that respond poorly to immunotherapy including immune checkpoint inhibition. This resistance may arise from an immunocompromised microenvironment and deficient immune recognition of tumor cells because of low mutational burden. The most prominent genetic a...

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Detalles Bibliográficos
Autores principales: Sørensen, Mia D., Nielsen, Ole, Reifenberger, Guido, Kristensen, Bjarne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412096/
https://www.ncbi.nlm.nih.gov/pubmed/33244787
http://dx.doi.org/10.1111/bpa.12921