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The presence of TIM‐3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status
Diffuse gliomas are aggressive brain tumors that respond poorly to immunotherapy including immune checkpoint inhibition. This resistance may arise from an immunocompromised microenvironment and deficient immune recognition of tumor cells because of low mutational burden. The most prominent genetic a...
Autores principales: | Sørensen, Mia D., Nielsen, Ole, Reifenberger, Guido, Kristensen, Bjarne W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412096/ https://www.ncbi.nlm.nih.gov/pubmed/33244787 http://dx.doi.org/10.1111/bpa.12921 |
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