Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines

Self-amplifying RNA (saRNA) is a next-generation vaccine platform, but like all nucleic acids, requires a delivery vehicle to promote cellular uptake and protect the saRNA from degradation. To date, delivery platforms for saRNA have included lipid nanoparticles (LNP), polyplexes and cationic nanoemu...

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Detalles Bibliográficos
Autores principales: Blakney, Anna K., McKay, Paul F., Hu, Kai, Samnuan, Karnyart, Jain, Nikita, Brown, Andrew, Thomas, Anitha, Rogers, Paul, Polra, Krunal, Sallah, Hadijatou, Yeow, Jonathan, Zhu, Yunqing, Stevens, Molly M., Geall, Andrew, Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412240/
https://www.ncbi.nlm.nih.gov/pubmed/34418521
http://dx.doi.org/10.1016/j.jconrel.2021.08.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412240/
https://www.ncbi.nlm.nih.gov/pubmed/34418521
http://dx.doi.org/10.1016/j.jconrel.2021.08.029

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