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Epigenetic instability may alter cell state transitions and anticancer drug resistance
Drug resistance is a significant obstacle to successful and durable anti-cancer therapy. Targeted therapy is often effective during early phases of treatment; however, eventually cancer cells adapt and transition to drug-resistant cells states rendering the treatment ineffective. It is proposed that...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412323/ https://www.ncbi.nlm.nih.gov/pubmed/34424912 http://dx.doi.org/10.1371/journal.pcbi.1009307 |