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Epigenetic instability may alter cell state transitions and anticancer drug resistance

Drug resistance is a significant obstacle to successful and durable anti-cancer therapy. Targeted therapy is often effective during early phases of treatment; however, eventually cancer cells adapt and transition to drug-resistant cells states rendering the treatment ineffective. It is proposed that...

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Detalles Bibliográficos
Autores principales:	Saini, Anshul, Gallo, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412323/ https://www.ncbi.nlm.nih.gov/pubmed/34424912 http://dx.doi.org/10.1371/journal.pcbi.1009307

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