Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells

The interaction of extracellular matrix (ECM) components with hepatic stellate cells (HSCs) is thought to perpetuate fibrosis by stimulating signaling pathways that drive HSC activation, survival and proliferation. Consequently, disrupting the interaction between ECM and HSCs is considered a therape...

Descripción completa

Detalles Bibliográficos
Autores principales: Freise, Christian, Lee, Hyunho, Chronowski, Christopher, Chan, Doug, Cziomer, Jessica, Rühl, Martin, Dagdelen, Tarkan, Lösekann, Maik, Erben, Ulrike, Catic, Andre, Tegge, Werner, Schuppan, Detlef, Somasundaram, Rajan, Sahin, Ergun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412337/
https://www.ncbi.nlm.nih.gov/pubmed/34473704
http://dx.doi.org/10.1371/journal.pone.0254557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412337/
https://www.ncbi.nlm.nih.gov/pubmed/34473704
http://dx.doi.org/10.1371/journal.pone.0254557

Ejemplares similares