Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells

During late embryonic development of the cerebral cortex, the major class of cortical output neurons termed subcerebral projection neurons (SCPN; including the predominant population of corticospinal neurons, CSN) and the class of interhemispheric callosal projection neurons (CPN) initially express...

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Detalles Bibliográficos
Autores principales: Sadegh, Cameron, Ebina, Wataru, Arvanites, Anthony C., Davidow, Lance S., Rubin, Lee L., Macklis, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412356/
https://www.ncbi.nlm.nih.gov/pubmed/34473715
http://dx.doi.org/10.1371/journal.pone.0254113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412356/
https://www.ncbi.nlm.nih.gov/pubmed/34473715
http://dx.doi.org/10.1371/journal.pone.0254113

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