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Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors

[Image: see text] Natural compounds that either increase or decrease polymerization of actin into filaments have become indispensable tools for cell biology. However, to date, it was not possible to use them as therapeutics due to their overall cytotoxicity and their unfavorable pharmacokinetics. Fu...

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Detalles Bibliográficos
Autores principales: Wang, Shuaijun, Meixner, Maximilian, Yu, Lushuang, Zhuo, Ling, Karmann, Lisa, Kazmaier, Uli, Vollmar, Angelika M., Antes, Iris, Zahler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412923/
https://www.ncbi.nlm.nih.gov/pubmed/34497907
http://dx.doi.org/10.1021/acsomega.1c02838