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Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors
[Image: see text] Natural compounds that either increase or decrease polymerization of actin into filaments have become indispensable tools for cell biology. However, to date, it was not possible to use them as therapeutics due to their overall cytotoxicity and their unfavorable pharmacokinetics. Fu...
Autores principales: | Wang, Shuaijun, Meixner, Maximilian, Yu, Lushuang, Zhuo, Ling, Karmann, Lisa, Kazmaier, Uli, Vollmar, Angelika M., Antes, Iris, Zahler, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412923/ https://www.ncbi.nlm.nih.gov/pubmed/34497907 http://dx.doi.org/10.1021/acsomega.1c02838 |
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