Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages

Macrophages undergo programmatic changes with age, leading to altered cytokine polarization and immune dysfunction, shifting these critical immune cells from protective sentinels to disease promoters. The molecular mechanisms underlying macrophage inflammaging are poorly understood. Using an unbiase...

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Detalles Bibliográficos
Autores principales: Santeford, Andrea, Lee, Aaron Y, Sene, Abdoulaye, Hassman, Lynn M, Sergushichev, Alexey A, Loginicheva, Ekaterina, Artyomov, Maxim N, Ruzycki, Philip A, Apte, Rajendra S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412946/
https://www.ncbi.nlm.nih.gov/pubmed/34423778
http://dx.doi.org/10.7554/eLife.66703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412946/
https://www.ncbi.nlm.nih.gov/pubmed/34423778
http://dx.doi.org/10.7554/eLife.66703

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