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Computational Analysis of the Nicotine Oxidoreductase Mechanism by the ONIOM Method
[Image: see text] Nicotine oxidoreductase (NicA2) is a monoamine oxidase (MAO)-based flavoenzyme that catalyzes the oxidation of S-nicotine into N-methylmyosmine. Due to its nanomolar binding affinity toward nicotine, it is seen as an ideal candidate for the treatment of nicotine addiction. Based on...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412962/ https://www.ncbi.nlm.nih.gov/pubmed/34497931 http://dx.doi.org/10.1021/acsomega.1c03357 |