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Reelin Regulates Neuronal Excitability through Striatal-Enriched Protein Tyrosine Phosphatase (STEP(61)) and Calcium Permeable AMPARs in an NMDAR-Dependent Manner

Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles. Aβ oligomers cause synaptic dysfunction early in AD by enhancing long-term depression (LTD; a paradigm for forgetfulness) via metabotropic glutam...

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Detalles Bibliográficos
Autores principales: Durakoglugil, Murat S., Wasser, Catherine R., Wong, Connie H., Pohlkamp, Theresa, Xian, Xunde, Lane-Donovan, Courtney, Fritschle, Katja, Naestle, Lea, Herz, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412985/
https://www.ncbi.nlm.nih.gov/pubmed/34290083
http://dx.doi.org/10.1523/JNEUROSCI.0388-21.2021