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Reelin Regulates Neuronal Excitability through Striatal-Enriched Protein Tyrosine Phosphatase (STEP(61)) and Calcium Permeable AMPARs in an NMDAR-Dependent Manner
Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles. Aβ oligomers cause synaptic dysfunction early in AD by enhancing long-term depression (LTD; a paradigm for forgetfulness) via metabotropic glutam...
Autores principales: | Durakoglugil, Murat S., Wasser, Catherine R., Wong, Connie H., Pohlkamp, Theresa, Xian, Xunde, Lane-Donovan, Courtney, Fritschle, Katja, Naestle, Lea, Herz, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412985/ https://www.ncbi.nlm.nih.gov/pubmed/34290083 http://dx.doi.org/10.1523/JNEUROSCI.0388-21.2021 |
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