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Cancer cells escape p53’s tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation
The inactivation of tumor-suppressor genes contributes heavily to oncogenesis. The mutation of TP53 has been well-studied and recognized as a major factor in the development of tumors. Yet other means of p53 inactivation has not been well-elucidated. We previously identified a hypermethylated gene Z...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413129/ https://www.ncbi.nlm.nih.gov/pubmed/34282274 http://dx.doi.org/10.1038/s41388-021-01949-5 |